ENTRIL 20 ORAL
ready to use clear aqueous oral solution containing
200 mg/ml enrofloxacin.
is a synthetic, broad spectrum antimicrobial, bactericidal
in action and effective against a wide range of gram
positive and gram negative bacteria as well as mycoplasmas. It
is indicated for use in Turkeys, Broilers, Broiler
breeders, and Replacement Chickens, for diseases
of the respiratory and alimentary tract, of bacterial
or mycoplasmal origin, e.g. pasteurellosis, mycoplasmosis,
coli-bacillosis, coli-septicaemia and salmonellosis,
where clinical experience, supported where possible
by sensitivity testing of the causal organism, indicates
enrofloxacin as the drug of choice.
DOSAGE AND ADMINISTRATION:
20 ORAL is administered via the drinking water.
• Medicated water
should be made up immediately prior to administration.
• Medication of
the water supply should be continuous during the
treatment period and no other source of water should be available.
• The dose rate
is 10 mg per kg bodyweight, daily for 3 to 10 days. Carefully
calculate the total body mass to be treated and the
total daily water consumption. Under normal conditions
0.25 ml / litre (50 ppm) is sufficient. Mature
birds such as breeders may require 0.50 ml / litre
• ENTRIL 20 ORAL
may be put directly into the header tank or introduced
via a water proportioner pump.
• For the treatment
of salmonellosis or pasteurellosis a treatment period
of 5 to 10 days must be used. For other conditions
the duration of treatment may be 3 to 5 days.
animal treatment only.
OUT OF THE REACH OF CHILDREN.
not exceed the recommended dose.
impervious gloves when handling the product.
any splashes from skin or eyes immediately with water.
hands and exposed skin after use.
not eat, drink, or smoke whilst using the product.
not use in poultry producing eggs for human consumption.
not administer to replacement birds within 14 days
of coming into lay.
must not be slaughtered for human consumption during
treatment or for 8 days following withdrawal of treatment.
below 25 degrees Centigrade in a dry place away from
withdrawal of the first dose, use the product within
Medicated water should be made up on a daily basis. Any
medicated water remaining after 24 hours must be
ml, 250 ml, 500 ml, and 1 litre plastic bottles.
pharmacokinetics of enrofloxacin are such that both
oral and parenteral administration lead to similar
serum levels. Enrofloxacin possesses a high distribution
volume. Tissue levels 2-3 times higher than that
found in the serum have been demonstrated in laboratory
animals and target species. Organs in which
high levels cab be expected are the lungs, liver,
kidney, bone, and lymphatic system.
Enrofloxacin also distributes into the C.S.F., the
aqueous humour, and the foetus in pregnant animals.